Optical Imaging

Current RFI publications
Abstracts
Selected Publications in Prestigious Journals Based on OI Brain Imagers
Reviews
Selected Publications of the Founders in the Field of Optical Imaging
Selected Publications in the Field of Imaging of Metabolic Responses
Selected references - Dyes


Current RFI publications
  • Grinvald A, Bonhoeffer T, Vanzetta I, et al. High-resolution functional optical imaging: from the neocortex to the eye. Ophthalmol Clin North Am. Mar 2004;17(1):53-67.
  • Nelson DA, Krupsky S, Pollack A, et al. Special report: Noninvasive multi-parameter functional optical imaging of the eye. Ophthalmic Surg Lasers Imaging. Jan-Feb 2005;36(1):57-66.
  • Landa G, Garcia PM, Rosen RB. Correlation between Retina Blood Flow Velocity Assessed by Retinal Function Imager and Retina Thickness Estimated by Scanning Laser Ophthalmoscopy/Optical Coherence Tomography. Ophthalmologica. Jan 12 2009;223(3):155-161.
  • Izhaky D, Nelson DA, Burgansky-Eliash Z, Grinvald A. Functional Imaging Using the Retinal Function Imager: Direct Imaging of Blood Velocity, achieving Fluorescein Angiography-like Images Without any Contrast Agent, Qualitative Oximetry and Functional Metabolic Signals. Japanese Journal of Ophthalmology. 2009 53:345-351.
  • Landa G, Rosen RB. New Patterns of Retinal Collateral Circulation are Exposed by the Retinal Functional Imager (RFI). Br J Ophthalmol. 2010;94:54-58.
  • Landa G, Rosen RB. A New Vascular Pattern for Idiopathic Juxtafoveal Telangiectasia Revealed by the Retinal Function Imager. Ophthalmic Surg Lasers Imaging. Jan-Feb 2010;41(3).
  • Burgansky-Eliash Z, Nelson DA, Bar-Tal Pupko O, Lowenstein A, Grinvald A, Barak A. Reduced Retinal Blood Flow Velocity in Diabetic Retinopathy. Retina 2010: 30(5):765-773.
  • Landa G, Amde W, Haileselassie Y, Rosen RB. Cilioretinal arteries in diabetic eyes are associated with increased retinal blood flow velocity and occurrence of diabetic macular edema. Retina. 2011 Feb;31(2):304-11.
  • Burgansky-Eliash Z, Barash H, Nelson DA, et al. Retinal Function Imager Measurements of Retinal Blood Flow Velocity in Patients with Early Diabetes Mellitus. Retina in press.
  • Darin A. Nelson, Amit Ruf, Oaknin Jacob, Zvia Burgansky-Eliash, Hila Barash, David Izhaky, Anat Lowenstein, Adiel Barak, Elisha Bartov, Tali Rock, Amiram Grinvald. High-Resolution Imaging of Perfused Capillaries Without the Use of Contrast Agent. Submitted.
  • Barash H, Burgansky-Eliash Z, Nelson DA, Izhaky D, Barak A, Lowenstein A, Neuderfer M, Kesler A, Grinvald A. Retinal Function Imager Measurements of Retinal Blood Flow Velocity and their Relationship to Various Physiological Parameters. Submitted.
  • Adiel Barak, Zvia Burgansky-Eliash, Hila Barash, Darin A. Nelson, Amiram Grinvald, Anat Lowenstein. The Effect of Intravitreal Bevacizumab (Avastin) Injection on Retinal Blood Flow Velocity. Submitted.
  • Beutelspacher SC. Serbecic N. Barash H. Burgansky-Eliash Z. Grinvald A. Jonas JB (2011) Central serous chorioretinopathy shows reduced retinal circulation in retinal function imaging (RFI) Acta Ophthalmologica 23 DOI: 10.1111/j.1755-3768.



Abstracts
ARVO 2011
SOE 2011
ARVO 2010
AAO 2009
ARVO & ISIE 2009

ARVO 2011
  • Adam M. Dubis, Ben R. Hansen, Robert F. Cooper, Joseph Beringer, Yusufu Sulai, Alfredo Dubra, Joseph Carroll1. The Relationship Between the Foveal Avascular Zone and Foveal Pit Morphology. Invest. Ophthalmol. Vis. Sci. 2011 52: ARVO E-Abstract 1045.
  • Kaare Christian, Zvia Burgansky-Eliash, Hila Barsh, Darin A. Nelson, Amiram Grinvald, Anat Lowenstein, Adiel Barak. Temporal and Nasal Retinal Blood flow Velocity Differences Detected by the Retinal Function Imager (RFI). Invest. Ophthalmol. Vis. Sci. 2011 52: ARVO E-Abstract 2134.
  • Zvia Burgansky-Eliash, Shay Gutfreund, Hila Barash, Elena Izkhakov, Ardon Rubinstein. Retinal Blood Flow Velocity in Patients with Metabolic Syndrome Using the RFI. Invest. Ophthalmol. Vis. Sci. 2011 52: ARVO E-Abstract 2135.
  • Lauren R. Schneider, Krishna Mukkamala, Leigh Spielberg, Gannady Landa, Katy Tai, Carmen Vasquez, Richard Rosen. Macular and Peri-papillary Retinal Blood Flow Velocities in Pseudoexfoliation Syndrome using the Retinal Functional Imager (RFI). Invest. Ophthalmol. Vis. Sci. 2011 52: ARVO E-Abstract 2898.
  • Sami S. Rezeq, Kapil M. Sampat, Jay Chhablani, Sunir J. Garg, William R. Freeman, Julia A. Haller, Andre J. Witkin, Dirk-Uwe G. Bartsch. Comparative Analysis of the Macula in Normal and Pathologic Eyes Using The Retinal Function Imager (RFI), a Novel, Non-Invasive Imaging Technique. Invest. Ophthalmol. Vis. Sci. 2011 52: ARVO E-Abstract 2899.
  • Chavakij BHOOMIBUNCHOO, Nicole Scripsema, Gennady Landa, Richard B. Rosen. Retinal Function Imaging for Evaluating of Changes in Retinal Blood Flow after Pan-retinal Laser Photocoagulation in Patients with Proliferative Diabetic Retinopathy. Invest. Ophthalmol. Vis. Sci. 2011 52: ARVO E-Abstract 2902.
  • Valerie Trubnik, Ruojin Ren, Nicole Scripsema, Syril K. Dorairaj, Carlos Gustavo De Moraes, Sung C. Park, Christopher Teng, Richard B. Rosen, Celso Tello1, Robert Ritch. Comparison of Retinal Blood Flow Velocities in Normal Tension Glaucoma (NTG) and High Tension Glaucoma (HTG) using the Retinal Functional Imager (RFI). Invest. Ophthalmol. Vis. Sci. 2011 52: ARVO E-Abstract 3474.
  • Nicole Scripsema, Syril Dorairaj, Ruojin Ren, Sung Chul Park, Gennady Landa, Katy Tai, Paul A. Sidoti, Richard B. Rosen, Robert Ritch. Effect of β-Zone Parapapillary Atrophy (βPPA) on Retinal Blood Flow Velocity in Primary Open-Angle Glaucoma (POAG) and Exfoliative Glaucoma (XFG). Invest. Ophthalmol. Vis. Sci. 2011 52: ARVO E-Abstract 3477.
  • Kasra Eliasieh, Nicole Scripsema, Syril Dorairaj, Gennady Landa, Katy W. Tai, Paul Sidoti, Adrianne Monsef, Carmen Vasquez, Richard B. Rosen. Peripapillary Blood Flow And β-Zone Parapapillary Atrophy in Primary Open-Angle Glaucoma. Invest. Ophthalmol. Vis. Sci. 2011 52: ARVO E-Abstract 3487.
  • Jiro Ueda, Miho Nozaki, Yuichiro Ogura. Effect of Topical Nipradilol on Retinal Microcirculation Evaluated by Retinal Function Imager. Invest. Ophthalmol. Vis. Sci. 2011 52: ARVO E-Abstract 3493.
  • Darin A. Nelson, Amiram Grinvald, Alina Sorkin, Amit Ruf, Zvia Burgansky-Eliash, Adiel Barak, Anat Lowenstein. The Size of Retinal Avascular Areas Measured with Non-invasive RFI and Flourescein Angiography. Invest. Ophthalmol. Vis. Sci. 2011 52: ARVO E-Abstract 4473.
  • Amiram Grinvald, Zvia Burgansky-Eliash, Darin A. Nelson, Hila Barash, Adiel Barak, Anat Lowenstein. Non-invasive Detailed Imaging of the Vascular Network Combined with Oral Flourescein Angiography. Invest. Ophthalmol. Vis. Sci. 2011 52: ARVO E-Abstract 4798.




SOE 2011
  • Z. Burgansky-Eliash, D.A. Nelson, A. Sorkin, H. Barash, A. Lowenstein, A. Barak, A. Grinvald. Comparison of retinal avascular zones detected by Flourescein Angiography and non-invasive Retinal Function Imager. Electronic poster




ARVO 2010




AAO 2009
  • Barak A, Burgansky-Eliash Z, Nelson DA, Neudorfer M, Barash H, Lowenstein A, Grinvald A. Retinal Blood Flow Velocity is Faster in Patients With Early Diabetes Mellitus Compared to Normal Subjects. PO603



ARVO & ISIE 2009

 


Selected Publications in Prestigious Journals Based on OI Brain Imagers
  • Palagina G, Eysel UT and Jancke D (2009) Strengthening of lateral activation in adult rat visual cortex after retinal lesions captured with voltage-sensitive dye imaging in vivo, PNAS 106 (21):1743-1747.
  • MacEvoy, SP, Tucker TR and Fitzpatrick D (2009) A precise form of divisive suppression supports population coding in the primary visual cortex, Nature Neuroscience 12 (5): 637-645.
  • Livneh Y, Feinstein N, Klein M and Mizrahi A (2009) Sensory Input Enhances Synaptogenesis of Adult-Born Neurons, Journal of Neuroscience 29 (1): 86? 97.
  • Li Y, Van Hooser SD, Mazurek M, White LE and Fitzpatrick D (2008) Experience with moving visual stimuli drives the early development of cortical direction selectivity, Nature 456 (7224): 952-956.
  • Chen G, Lu HD and Roe AW (2008) A Map for Horizontal Disparity in Monkey V2, Neuron 58 (3):442-450.
  • Nauhaus I., Benucci A, Carandini M and Ringach DL (2008) Neuronal Selectivity and Local Map Structure in Visual Cortex, Neuron 57 (5): 673-679.
  • Kerr JND,de Kock CPJ, Greenberg DS, Bruno RM, Sakmann B. and Helmchen F (2007) Spatial Organization of Neuronal Population Responses in Layer 2/3 of Rat Barrel Cortex, Journal of Neuroscience 27 (48): 13316-13328.
  • Farley, BJ, Yu H, Jin DZ and Sur M (2007) Alteration of Visual Input Results in a Coordinated Reorganization of Multiple Visual Cortex Maps, Journal of Neuroscience 27 (38): 10299-10310.
  • Chen LM, Turner GH, Friedman RM, Zhang N, Gore JC, Roe AW and Avison MJ (2007) High-Resolution Maps of Real and Illusory Tactile Activation in Primary Somatosensory Cortex in Individual Monkeys with Functional Magnetic Resonance Imaging and Optical Imaging, Journal of Neuroscience 27 (34): 9181-9191.
  • Accolla R, Bathellier B, Petersen CCH and Carleton Alan (2007) Differential Spatial Representation of Taste Modalities in the Rat Gustatory Cortex, Journal of Neuroscience 27 (6): 1396-1404.
  • Xu X, Collins CE, Khaytin I, Kaas JH and Casagrande VA (2006) Unequal representation of cardinal vs. oblique orientations in the middle temporal visual area, PNAS 103 (46): 17490-17495.
  • Chen Y, Geisle WS and Seidemann E (2006) Optimal decoding of correlated neural population responses in the primate visual cortex, Nature Neuroscience 9 (11): 1412?1420.
  • Ohki K, Chung S, Kara, P, Hubener M, Bonhoeffer T and Reid RC (2006) Highly ordered arrangement of single neurons in orientation pinwheels, Nature 442 (7105): 925-928.
  • Lin DY, Shea SD, Katz LC (2006) Representation of Natural Stimuli in the Rodent Main Olfactory Bulb, Neuron 50 (6): 937-949.
  • Hofer SB, Mrsic-Flogel TD, Bonhoeffer T and Hübener M (2005) Prior experience enhances plasticity in adult visual cortex, Nature Neuroscience 9 (1): 127-132.
  • Roe AW, Lu HD and Hung CP (2005) Cortical processing of a brightness illusion, PNAS 2005 102 (10): 3869-3874.
  • Van Hooser SD, Heimel, JAF, Chung S, Nelson SB and Toth LJ (2005) Orientation Selectivity without Orientation Maps in Visual Cortex of a Highly Visual Mammal, Journal of Neuroscience 25 (1): 19-28.
  • Vanzetta I, Slovin H, Omer DB, et al. Columnar resolution of blood volume and oximetry functional maps in the behaving monkey: Implications for fMRI Neuron42 (5): 843-854 jun 10 2004
  • Eysel UT. Illusions and perceived images in the primate brain Science 302 (5646): 789-791 oct 31 2003
  • Petersen CCH, Grinvald A, Sakmann B. Spatiotemporal dynamics of sensory responses in layer 2/3 of rat barrel cortex measured in vivo by voltage-sensitive dye imaging combined with whole-cell voltage recordings and neuron reconstructions. Journal Of Neuroscience 23 (4): 1298-1309 feb 15 2003
  • Tucker TR, Katz LC. Spatiotemporal patterns of excitation and inhibition evoked by the horizontal network in layer 2/3 of ferret visual cortex. JOURNAL OF NEUROPHYSIOLOGY 89 (1): 488-500 JAN 2003
  • Bosking WH, Crowley JC, Fitzpatrick D (2002). Spatial coding of position and orientation in primary visual cortex. Nat Neuroscience, 5:874-882.
  • Luo M, Katz LC (2001). Response correlation maps of neurons in the mammalian olfactory bulb. Neuron, 32: 1165-1179.
  • Schwartz TH, Bonhoeffer T (2001). In vivo optical mapping of epileptic foci and surround inhibition in ferret cerebral cortex. Nature Med, 7:1063-1067.
  • Dragoi V, Rivadulla C, Sur M (2001). Foci of orientation plasticity in visual cortex. Nature, 411: 80-6.
  • Rubin BD, Katz LC (2001). Spatial coding of enantiomers in the rat olfactory bulb. Nature Neurosci, 4: 355-6.
  • Uchida N, Takahashi YK, Tanifuji M, Mori K (2000). Odor maps in the mammalian olfactory bulb: domain organization and odorant structural features. Nature Neurosci, 3:1035-43.
  • von Melchner L, Pallas SL, Sur M (2000). Visual behaviour mediated by retinal projections directed to the auditory pathway. Nature, 404:871-6.
  • Grinvald A, Slovin H, Vanzetta I (2000). Non-invasive visualization of cortical columns by fMRI (2000). Nature Neurosci, 3:105-7.
  • Crowley JC, Katz LC. Early development of ocular dominance columns (2000). Science. 2000 290(5495):1321-4.
  • Sharma J, Angelucci A, Sur M (2000). Induction of visual orientation modules in auditory cortex (2000). Nature, 404: 841-7.
  • Das A, Gilbert CD (1999). Topography of contextual modulations mediated by short-range interactions in primary visual cortex. Nature, 399: 655-61.
  • Vanzetta I, Grinvald A (1999). Increased cortical oxidative metabolism due to sensory stimulation: implications for functional brain imaging. Science, 286: 1555-8.
  • Das A, and Gilbert CD (1997). Distortions of visuotopic map match orientation singularities in primary visual cortex. Nature, 387:594-598.
  • Crair MC, Gillespie DC, Stryker MP (1998). The role of visual experience in the development of columns in cat visual cortex. Science, 279:566-70.
  • Weliky, M. and Katz LC (1997). Disruption of orientation tuning in visual cortex by artificially correlated neuronal activity Nature, 386:680-685.
  • Maldonado PE, Godecke I, Gray CM, Bonhoeffer T (1997). Orientation selectivity in pinwheel centers in cat striate cortex. Science, 276:1551-5.
  • Shoham, D, Hubener, M, Grinvald A and Bonhoeffer T (1997). Spatio-temporal
    frequency domains and their relationship to cytochrome oxidase staining in cat visual cortex. Nature, 385: 529-534.
  • Godecke I, Bonhoeffer T (1996). Development of Identical Orientation Maps for 2 Eyes without Common Visual Experience, Nature, 379: 251-254.
  • Weliky M, Bosking W, Fitzpatrick D (1996). A systematic map of direction preference in primary visual cortex. Nature 379: 725-728.
  • Malonek D, and Grinvald A (1996). Interactions between electrical cortical activity and the microcirculation revealed by imaging spectroscopy: Implications for functional brain mapping. Science 272: 551-554.
  • Wang G, Tanaka K and Tanifuji M (1996). Optical imaging of functional
    organization in the monkey inferotemporal cortex. Science, 272: 1665-1668.
  • Sheth BR, Sharma J, Rao SC, and Sur M (1996). Orientation maps of subjective contours in visual cortex. Science 274: 2110-2115.
  • Das, A Gilbert, CD (1995). Long-range horizontal connections and their role in cortical reorganization revealed by optical recording of cat primary visual cortex. Nature, 375: 780.




Reviews
  • White LE and Fitzpatrick D (2007) Vision and Cortical Map Development, Neuron 56 (2): 327-338.
  • Neuroscience Research. Windhorst U and Johansson H (Editors) Springer Verlag, pp 893-969.
  • Hubener M, Bonhoeffer T. Visual cortex: Two-photon excitement Current Biology 15 (6): R205-R208 mar 29 2005
  • Grinvald A, Hildesheim R. VSDI: A new era in functional imaging of cortical dynamics. Nature Reviews Neuroscience 5 (11): 874-885 nov 2004
  • Zapeda A, Arias C, Sengpiel F. Optical imaging of intrinsic signals: recent developments in the methodology and its applications. Journal Of Neuroscience Methods 136 (1): 1-21 jun 15 2004
  • Grinvald A, et al. (1999). In-vivo Optical Imaging of cortical Architecture and Dynamics. In Modern Techniques in Neuroscience Research. U. Windhorst and H. Johansson Springer, pp 893-969
  • Mrsic-Flogel T, Hubener M, Bonhoeffer T. Brain mapping: New wave optical Imaging. C urrent B iology 13 (19): R778-R780 SEP 30 2003
  • Grinvald A (1985). Real-time optical mapping of neuronal activity: from single growth cones to the intact mammalian brain. Ann Rev Neurosci, 8: 263-305.





Selected Publications of the Founders in the Field of Optical Imaging
  • Grinvald A, Salzberg BM and Cohen LB (1977). Simultaneous recording from several neurons in an invertebrate central nervous system. Nature, 268: 140.
  • Grinvald A, Cohen LB, Lesher S and Boyle MB (1981). Simultaneous optical monitoring of activity of many neurons in invertebrate ganglia using a 124-element photodiode array. J Neurophysiol, 45: 829-840.
  • Grinvald A and Farber I (1981). Optical recording of calcium action potentials from growth cones of cultured neurons using a laser microbeam. Science, 212: 1164-1166.
  • Grinvald A, Hildesheim R, Farber IC and Anglister L (1982). Better fluorescent probes for the measurements of rapid changes in membrane potential. Biophys J, 39: 301-308.
  • Grinvald A, Manker A and Segal M (1982). Visualization of the spread of electrical activity in rat hippocampal slices by voltage-sensitive optical probes. J Physiol, 333: 269-291.
  • Grinvald A, Anglister L, Freeman JA, Hildesheim R and Manker A (1984). Real time optical imaging of naturally evoked electrical activity in the intact frog brain. Nature, 308: 848-850.
  • Ts'o DY, Frostig RD, Lieke E and Grinvald A (1990). Functional architecture of primate visual cortex revealed by high resolution optical imaging. Science, 249: 417-420.
  • Bonhoeffer T and Grinvald A (1991). Iso-orientation domains in cat visual cortex are arranged in pinwheel-like patterns. Nature, 353: 429-431.
  • Arieli A, Sterkin A, Grinvald A and Aertsen A (1996). Dynamics of on-going activity: Explanation of the large variability in evoked cortical responses. Science, 273: 1868-1871.
  • Shoham D, Hubener M, Grinvald A and Bonhoeffer T (1997). Spatio-temporal frequency domains and their relationship to cytochrome oxidase staining in cat visual cortex. Nature, 385: 529-534.
  • Shoham, D, Glaser DE, Arieli A, Kenet T, Hildesheim R, and Grinvald A (1999). Imaging cortical architecture and dynamics at high spatial and temporal resolution with new voltage-sensitive dyes. Neuron, 24: 1-12.
  • Tsodyks M, Kenet T, Grinvald A and Arieli A (1999). The spontaneous activity of single cortical neuron depends the underlying global functional architecture . Science, 286: 1943-1946.




Selected Publications in the Field of Imaging of Metabolic Responses
  • Ma H, Geneslaw A, Zhao M, Suh M, Perry C and Schwartz TH (2009). The importance of latency in the focality of perfusion and oxygenation changes associated with triggered after discharges in human cortex, Journal of Cerebral Blood Flow & Metabolism 29 (5), 1003?1014.
  • Zhao M, Suh M, Ma H, Perry C, Geneslaw A and Schwartz TH (2007). Focal Increases in Perfusion and Decreases in Hemoglobin Oxygenation Precede Seizure Onset in Spontaneous Human Epilepsy, Epilepsia 48 (11): 2059-2067.
  • Devor A, et al. (2007). Suppressed Neuronal Activity and Concurrent Arteriolar Vasoconstriction May Explain Negative Blood Oxygenation Level-Dependent Signal, Journal of Neuroscience 27 (16): 4452-4459.
  • Suh M, Bahar, S Mehta AD and Schwartz TH (2006) Blood volume and hemoglobin oxygenation response following electrical stimulation of human cortex, NeuroImage 31 (1): 66-75.
  • Suh M, Bahar, S Mehta AD and Schwartz TH (2005) Temporal Dependence in Uncoupling of Blood Volume and Oxygenation during Interictal Epileptiform Events in Rat Neocortex, Journal of Neuroscience 25 (1): 68-77.
  • Dunn AK, Devor A, Dale AM, et al. Spatial extent of oxygen metabolism and hemodynamic changes during functional activation of the rat somatosensory cortex (2005) Neuroimage 27 (2): 279-290.
  • Vanzetta I, Hildesheim R, Grinvald A. Compartment-resolved imaging of activity-dependent dynamics of cortical blood volume and oximetry (2005) Journal Of Neuroscience 25 (9): 2233-2244.
  • Logothetis NK, Pfeuffer J. On the nature of the BOLD fMRI contrast mechanism (2004). Magnetic Resonance Imaging 22 (10): 1517-1531.
  • Logothetis NK, Wandell BA. Interpreting the BOLD signal (2004). Annual Review of Physiology 66: 735-769.
  • Devor A, Dunn AK, Andermann ML, et al. Coupling of total hemoglobin concentration, oxygenation, and neural activity in rat somatosensory cortex (2003). Neuron 39 (2): 353-359.
  • Grinvald, A Slovin H and Vanzetta I (2000). Non-invasive visualization of Cortical Columns by f-MRI. Nature Neuroscience, 3: 105-107.
  • Vanzetta I and Grinvald A (1999). Cortical activity-dependent oxidative metabolism revealed by direct oxygen tension measurements; implications for functional brain imaging. Science, 286: 1555-1558.
  • Malonek D and Grinvald A (1996). Interactions between electrical activity and cortical microcirculation revealed by imaging spectroscopy; implications for functional brain imaging. Science, 272: 551-554.
  • Frostig RD, Lieke E, Ts'o DY and Grinvald A (1990). Cortical functional architecture and local coupling between neuronal activity and the microcirculation revealed by in vivo high resolution optical imaging of intrinsic signals in cat and monkey visual cortex. Proc Natl Acad Sci USA, 87: 6082-6086.
  • Grinvald A, Lieke E, Frostig R, Gilbert CD and Wiesel TN (1986). Functional architecture of cortex revealed by optical imaging of intrinsic signals. Nature, 324: 361-364.





Selected references - Dyes
  • Shien Wei Ng B, Grabska-Barwinska A, Gunturkun O and Jancke D (2010) Dominant Vertical Orientation Processing without Clustered Maps: Early Visual Brain Dynamics Imaged with Voltage-Sensitive Dye in the Pigeon Visual Wulst, Journal of Neuroscience 30 (19): 6713? 6725.
  • Benucci A, Ringach DL and Carandini M (2009) Coding of stimulus sequences by population responses in visual cortex, Nature Neuroscience 12 (10):1317-1324.
  • Benucci A, Frazor RA and Carandini M (2007) Standing Waves and Traveling Waves Distinguish Two Circuits in Visual Cortex, Neuron 55 (1): 103-117.
  • Jancke D, Chavane F, Naaman S, Grinvald A (2004). Imaging cortical correlates of illusion in early visual cortex. Nature, 2004 Mar 25;428(6981):423-6.
  • Kenet T, Bibitchkov D, Tsodyks M, Grinvald A, Arieli A (2003). Spontaneously emerging cortical representations of visual attributes. Nature, 2003 Oct 30;425(6961):954-6.
  • Derdikman D, Hildesheim R, Ahissar E, Arieli A, Grinvald A (2003). Imaging spatiotemporal dynamics of surround inhibition in the barrels somatosensory cortex. J Neurosci, 2003 Apr 15;23(8):3100-5.
  • Sharon D and Grinvald A (2002). Dynamics and constancy in cortical spatiotemporal patterns of orientation processing. Science, 295: 512-515.
  • Seidemann E, Arieli A, Grinvald A, Slovin H (2002). Dynamics of depolarization and hyperpolarization in the frontal cortex and saccade goal. Science, 295:862-865.
  • Spors H and Grinvald A (2002). Temporal dynamics of odor representations and coding by the mammalian olfactory bulb. Neuron, 34:1-20.
  • Slovin H., Arieli A, Hildesheim R, and Grinvald A (2002). Long-term voltage-sensitive dye imaging of cortical dynamics in the behaving monkey. J. Neurophys, In press.
  • Shoham, D, Glaser DE, Arieli A, Kenet T, Hildesheim R and Grinvald A (1999). Imaging cortical architecture and dynamics at high spatial and temporal resolution with new voltage-sensitive dyes. Neuron, 24:1-12.
  • Grinvald A, Lieke E, Frostig R, Gilbert CD and Wiesel TN (1986). Functional architecture of cortex revealed by optical imaging of intrinsic signals. Nature, 324: 361-364.
  • Grinvald A, Anglister L, Freeman JA, Hildesheim R and Manker A (1984). Real time optical imaging of naturally evoked electrical activity in the intact frog brain. Nature, 308:848-850.
  • Grinvald A., Fine A, Farber IC and Hildesheim R (1983). Fluorescence monitoring of electrical responses from small neurons and their processes. Biophys. J, 42:145-198.
  • Grinvald A, Manker A and Segal M (1982). Visualization of the spread of electrical activity in rat hippocampal slices by voltage-sensitive optical probes. J. Physiol, 333:269-291.
  • Carlson GC, Coulter DA (2008), In vitro functional imaging in brain slices using fast voltage-sensitive dye imaging combined with whole-cell patch recording,
    Nature Protocols 3 (2): 249-255 Jan 24 2008
  • Farkas E, Pratt R, Sengpiel F and Obrenovitch TP (2008) Direct, live imaging of cortical spreading depression and anoxic depolarisation using a fluorescent, voltage-sensitive dye,
    Journal of Cerebral Blood Flow & Metabolism 28, 251-262 2008
  • Ferezou I, Bolea S and Petersen CCH (2006) Visualizing the Cortical Representation of Whisker Touch: Voltage-Sensitive Dye Imaging in Freely Moving Mice,
    Neuron, 4 (50): 617-629 May 18 2006





 
Optical Imaging